Symptoms+and Diagnosis

 When blood vessels are injured platelets collect over the injured area and form a plug to prevent further bleeding. This plug is formed by a series of proteins, called clotting factors. People with hemophilia have a mutation in the F8 gene which provides instructions for the enzyme that produces clotting factor and their blood does not properly clot. Major symptoms of hemophilia A are excessive bleeding and easy bruising. Other symptoms that could be experienced: The most common place to have bleeding is the joints (knees, ankles, or elbows). Bleeding can also occur in the muscles, or digestive tract.
 * SYMPTOMS: **
 * bleeding for long period of time after an accident or injury
 * spontaneous bleeding

 The first step is to evaluate the symptoms and review the family history. Other tests include:
 * HOW TO DIAGNOSE HEMOPHILIA A: **
 * Physical examination
 * Intrauterine DNA testing
 * Molecular genetic testing
 * Blood test
 * Measure clotting factor level in the blood. If it is below 50 percent of normal, you probably are a carrier and have mild hemophilia.
 * Screening tests to show if the blood is clotting properly.

 A person can be healthy (with the gene to produce factor VIII), healthy but a carrier (female without the gene on one x-chromosome), or one with hemophilia A (female without the gene on both x-chromosomes or male without the gene on x-chromosome)